Born in Novate near Milan, he studied at the Breta Academy and at Magni's studio in Rome.
Settling in Rome, 1856, he specialised in portraits and figurative subjects from mythology and the Old Testament, usually in marble.
A good example of his work is Ruth, in Glasgow's Kibble Palace, Botanic Gardens (c. 1880), which was exhibited at the 1888 Kelvingrove International Exhibition and presented to the city by its lender, Leonard Gow, in 1927 (cat no. S.71).
A copy of Ruth is in the chateau of Kromeriz in the Czech Republic.
Ciniselli exhibited in Europe and Australia, and died in Rome.
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